Chirals

ChiralVision is a global provider of chiral process development and enzyme immobilization services to the pharmaceutical industry. Our services include route design to advanced intermediates such as unnatural amino acids and derivatives and active pharmaceutical ingredients. Using enzymatic technology the target optical purity for high quality chiral intermediates is >99% e.e. for single chiral centres and >98% d.e. for compounds with multiple chiral centers Various of these compounds are available as commercial product and listed below.

 

Products

Products:

- α-amino acids

- B-amino acids

- amines

Chirals

α-amino acids

Prod.  No.

Product name

[IUPAC]

Specifications

Structure

CV0601

D-Isoleucine

[(2R,3R)-2-amino-3-methylpentanoic acid]

H-D-Ile-OH

Form: C6H13NO2

MW: 131.17

Cas. No: 319-78-8

e.e.: 99 % ee

d.e.: 98 % ee

CV1101

BOC-D-Isoleucine      hemihydrate

[BOC-(2R,3R)-2-amino-3-methylpentanoic acid]

BOC-D-Ile-OH

F: C11H21NO4 .½H2O

MW: 231.29 +9

Cas. No: 55721-65-8

e.e.: 99 % ee

d.e.: 98 % ee

 

CV2101

FMOC-D-Isoleucine

[FMOC-(2R,3R)-2-amino-3-methylpentanoic acid]

FMOC-D-Ile-OH

Form: C21H23NO4

MW: 353.41

Cas. No: 143688-83-9

e.e.: 99 % ee

d.e.: 98 % ee

 

CV0602

L-allo-Isoleucine

[(2S,3R)-2-amino-3-methylpentanoic acid]

H-allo-Ile-OH

Form: C6H13NO2

MW: 131.17

Cas. No: 1509-34-8

e.e.: 99 % ee

d.e.: 98 % ee

CV1102

BOC-L-allo-Isoleucine

[BOC-(2S,3R)-2-amino-3-methylpentanoic acid]

BOC-allo-Ile-OH

Form: C11H21NO4

MW: 231.29

Cas. No: 35264-07-4

e.e.: 99 % ee

d.e.: 98 % ee

 

 

CV2102

FMOC-L-allo-Isoleucine

[FMOC-(2S,3R)-2-amino-3-methylpentanoic acid]

FMOC-allo-Ile-OH

Form: C21H23NO4

MW: 353.41

Cas. No: 251316-98-0

e.e.: 99 % ee

d.e.: 98 % ee

 

 

CV0603

D-allo-Isoleucine

[(2R,3S)-2-amino-3-methylpentanoic acid]

H-D-allo-Ile-OH

Form: C6H13NO2

MW: 131.17

Cas. No: 1509-35-9

e.e.: 99 % ee

d.e.: 98 % ee

 

CV1103

BOC-D-allo-Isoleucine

[BOC-(2R,3S)-2-amino-3-methylpentanoic acid]

BOC-D-allo-Ile-OH

Form: C11H21NO4

MW: 231.29

Cas. No: 55780-90-0

e.e.: 99 % ee

d.e.: 98 % ee

 

CV2103

FMOC-D-allo-Isoleucine

[FMOC-(2R,3S)-2-amino-3-methylpentanoic acid]

FMOC-D-allo-Ile-OH

Form: C21H23NO4

MW: 353.41

Cas. No: 118904-37-3

e.e.: 99 % ee

d.e.: 98 % ee

 

CV0604

D-tert-Leucine

[(R)-2-amino-3,3-dimethylbutanoic acid]

H-tBu-D-Gly-OH

H-D-Tle-OH

Form: C6H13NO2

MW: 131.17

Cas. No: 26782-71-8

e.e.:  >99 %

CV1106

BOC-D-tert-Leucine

[BOC-(R)-2-amino-3,3-dimethylbutanoic acid] 

Boc-tBu-D-Gly-OH

Boc-D-Tle-OH

Form: C11H21NO4

MW: 231.29

Cas. No: 124655-17-0

e.e.:  >99 %

 

CV2104

FMOC-D-tert-Leucine

[FMOC-(R)-2-amino-3,3-dimethylbutanoic acid]

Fmoc-tBu-D-Gly-OH

Fmoc-D-Tle-OH

Form: C21H23NO4

MW: 353.42

Cas. No: 198543-64-5

e.e.:  >99 %

 

CV0503

L-Norvaline

[(S)-2-Aminopentanoic acid]

Form: C5H11NO2

MW: 117.15

Cas. No: 6600-40-4

e.e.:  >99 %

CV1007

BOC-L-Norvaline

[BOC-(S)-2-Aminopentanoic acid]

Form: C10H19NO4

MW: 217.26

Cas. No: 53308-95-5

e.e.:  >99 %

 

CV2001

Fmoc-L-Norvaline

[FMOC-(S)-2-Aminopentanoic acid]

Form: C20H21NO4

MW: 339.39

Cas. No: 135112-28-6

e.e.:  >99 %

 

CV0504

D-Norvaline

[(R)-2-Aminopentanoic acid]

Form: C5H11NO2

MW: 117.15

Cas. No: 2013-12-9

e.e.:  >99 %

CV1008

BOC-D-Norvaline

[BOC-(R)-2-Aminopentanoic acid]

Form: C10H19NO4

MW: 217.26

Cas. No: 57521-85-4

e.e.:  >99 %

 

CV2002

Fmoc-D-Norvaline

[FMOC-(R)-2-Aminopentanoic acid]

Form: C20H21NO4

MW: 339.39

Cas. No: 144701-24-6

e.e.:  >99 %

 

 

β-amino acids

Prod.  No.

Product name

[IUPAC]

Specifications

Structure

CV0901

(R)-β-phenylalanine

[(R)-3-amino-3-phenylpropanoic acid]

Form: C9H11NO2

MW: 165.19

Cas. No: 13921-90-9

e.e.: 99%

CV1401

BOC-(R)-β-phenylalanine

[BOC-(3R)-3-amino-3-phenylpropanoic acid]

Form: C14H19NO4

MW: 265.31

Cas. No: 161024-80-2

e.e.: 99%

 

CV2401

FMOC-(R)-β-phenylalanine

[FMOC-(3R)-3-amino-3-phenylpropanoic acid]

Form: C24H21NO4

MW: 387.44

Cas. No: 220498-02-2

e.e.: 99%

 

CV1104

(R)-β-phenylalanine ethyl ester

[ethyl (3R)-3-amino-3-phenylpropionate]

Form: C11H15NO2

MW: 193.25

Cas. No: -

e.e.: 99%

 

CV0902

(S)-β-phenylalanine

[(S)-3-amino-3-phenylpropanoic acid]

Form: C9H11NO2

MW: 165.19

Cas. No: 40856-44-8

e.e.: >99 %

CV1402

BOC-S-β-phenylalanine

[BOC-(3S)-3-amino-3-phenylpropanoic acid]

Form: C14H19NO4

MW: 265.31

Cas. No: 103365-47-5

e.e.: >99 %

 

CV2402

FMOC-S-β-phenylalanine

[FMOC-(3S)-3-amino-3-phenylpropanoic acid]

Form: C24H21NO4

MW: 387.44

Cas. No: 209252-15-3

e.e.: >99 %

 

CV1105

(S)-β-phenylalanine ethyl ester

[ethyl (3R)-3-amino-3-phenylpropionate]

Form: C11H15NO2

MW: 193.25

Cas. No: -

e.e.: >99 %

 

CV0903

(R)-ß-(p-chlorophenyl)alanine

[(R)-3-Amino-3-(4-chloro-phenyl)-propionic acid]

Form: C9H10NO2Cl

MW: 199.64

Cas. No: 131690-61-4

e.e.: >>98 %

CV1403

BOC-(R)-ß-(p-chlorophenyl)alanine

[BOC-(R)-3-Amino-3-(4-chloro-phenyl)-propionic acid]

Form: C14H18ClNO4

MW: 299.75

Cas. No: 479064-93-2

e.e.: >>98 %

 

CV2403

FMOC-(R)-ß-(p-chlorophenyl)alanine

[FMOC-(R)-3-Amino-3-(4-chloro-phenyl)-propionic acid]

Form: C24H20ClNO4

MW: 421.88

Cas. No: 479064-92-1

e.e.: >>98 %

 

CV1107

(R)-ß-(p-chlorophenyl)alanine ethyl ester

[ethyl (R)-3-Amino-3-(4-chloro-phenyl)-propionate]

Form: C11H14ClNO2

MW: 227.69

Cas. No: -

e.e.: >>98 %

 

CV0904

(S)-ß-(p-chlorophenyl)alanine

[(S)-3-Amino-3-(4-chloro-phenyl)-propionic acid]

Form: C9H10NO2Cl

MW: 199.64

Cas. No: 131690-60-3

e.e.: >>98 %

CV1404

BOC-(S)-ß-(p-chlorophenyl)alanine

[BOC-(S)-3-Amino-3-(4-chloro-phenyl)-propionic acid]

Form: C14H18ClNO4

MW: 299.75

Cas. No: 479064-90-9

e.e.: >>98 %

 

CV2404

FMOC-(S)-ß-(p-chlorophenyl)alanine

[FMOC-(S)-3-Amino-3-(4-chloro-phenyl)-propionic acid]

Form: C24H20ClNO4

MW: 421.88

Cas. No: 479064-91-0

e.e.: >>98 %

 

CV1108

(S)-ß-(p-chlorophenyl)alanine ethyl ester

[ethyl (S)-3-Amino-3-(4-chloro-phenyl)-propionate]

Form: C11H14ClNO2

MW: 227.69

Cas. No: -

e.e.: >>98 %

 

CV1003

(R)-ß-(p-methylphenyl)alanine

[(R)-3-Amino-3-(4-methyl-phenyl)-propionic acid]

Form: C10H13NO2

MW: 179.22

Cas. No: 479064-87-4

e.e.: >99 %

CV1503

BOC-(R)-ß-(p-methylphenyl)alanine

[BOC-(R)-3-Amino-3-(4-methyl-phenyl)-propionic acid]

Form: C15H21NO4

MW: 279.33

Cas. No: 479064-97-6

e.e.: >99 %

 

CV2503

FMOC-(R)-ß-(p-methylphenyl)alanine

[FMOC-(R)-3-Amino-3-(4-methyl-phenyl)-propionic acid]

Form: C25H23NO4

MW: 401.45

Cas. No: 479064-98-7

e.e.: >99 %

 

CV1203

(R)-ß-(p-methylphenyl)alanine ethyl ester

[ethyl (R)-3-Amino-3-(4-methyl-phenyl)-propionate]

Form: C12H17NO2

MW: 207.27

Cas. No: -

e.e.: >99 %

 

CV1004

(S)-ß-(p-methylphenyl)alanine

[(S)-3-Amino-3-(4-methyl-phenyl)-propionic acid]

Form: C10H13NO2

MW: 179.22

Cas. No: 479065-00-4

e.e.: >99 %

CV1504

BOC-(S)-ß-(p-methylphenyl)alanine

[BOC-(S)-3-Amino-3-(4-methyl-phenyl)-propionic acid]

Form: C15H21NO4

MW: 279.33

Cas. No: 479064-96-5

e.e.: >99 %

 

CV2504

FMOC-(S)-ß-(p-methylphenyl)alanine

[FMOC -(S)-3-Amino-3-(4-methyl-phenyl)-propionic acid]

Form: C25H23NO4

MW: 401.45

Cas. No: 479064-99-8

e.e.: >99 %

 

CV1204

(S)-ß-(p-methylphenyl)alanine ethyl ester

[ethyl (S)-3-Amino-3-(4-methyl-phenyl)-propionate]

Form: C12H17NO2

MW: 207.27

Cas. No: -

e.e.: >99 %

 

CV1001

(R)-β-(p-methoxyphenyl)alanine

[(R)-3-Amino-3-(4-methoxy-phenyl)-propionic acid]

Form: C10H13NO3

MW: 195.22

Cas. No: 131690-57-8

e.e.: >99 %

CV1501

BOC-(R)-β-(p-methoxyphenyl)alanine

[BOC-(R)-3-Amino-3-(4-methoxy-phenyl)-propionic acid]

Form: C15H21NO5

MW: 295.33

Cas. No: 500788-87-4

e.e.: >99 %

 

CV2501

FMOC-(R)-β-(p-methoxyphenyl)alanine

[FMOC-(R)-3-Amino-3-(4-methoxy-phenyl)-propionic acid]

Form: C25H23NO5

MW: 417.46

Cas. No: 511272-33-6

e.e.: >99 %

 

CV1201

(R)-β-(p-methoxyphenyl)alanine ethyl ester

[ethyl (R)-3-Amino-3-(4-methoxy-phenyl)-propionate]

Form: C12H17NO3

MW: 223.27

Cas. No: -

e.e.: >99 %

 

CV1002

(S)-β-(p-methoxyphenyl)alanine

[(S)-3-Amino-3-(4-methoxy-phenyl)-propionic acid]

Form: C10H13NO3

MW: 195.22

Cas. No: 131690-56-7

e.e.: >98 %

CV1502

BOC-(S)-β-(p-methoxyphenyl)alanine

[BOC-(S)-3-Amino-3-(4-methoxy-phenyl)-propionic acid]

Form: C15H21NO5

MW: 295.33

Cas. No: -

e.e.: >98 %

 

CV2502

FMOC-(S)-β-(p-methoxyphenyl)alanine

[FMOC-(S)-3-Amino-3-(4-methoxy-phenyl)-propionic acid]

Form: C25H23NO5

MW: 417.46

Cas. No: -

e.e.: >98 %

 

CV1202

(S)-β-(p-methoxyphenyl)alanine ethyl ester

[ethyl (S)-3-Amino-3-(4-methoxy-phenyl)-propionate]

Form: C12H17NO3

MW: 223.27

Cas. No: -

e.e.: >98 %

 

CV0701

(R)-3-Amino-3-(2-thienyl)-propionic acid

Form: C7H9NO2S

MW: 171.22

Cas. No: 73495-10-0

CV1205

Boc-(R)-3-Amino-3-(2-thienyl)-propionic acid

Form: C12H17NO4S

MW: 271.33

Cas. No: n.a.

 

CV2201

Fmoc-(R)-3-Amino-3-(2-thienyl)-propionic acid

Form: C22H19NO4S

MW: 393.46

Cas. No: n.a.

 

CV0702

(S)-3-Amino-3-(2-thienyl)-propionic acid

Form: C7H9NO2S

MW: 171.22

Cas. No: 131829-50-0

CV1206

Boc-(S)-3-Amino-3-(2-thienyl)-propionic acid

Form: C12H17NO4S

MW: 271.33

Cas. No: n.a.

 

CV2202

Fmoc-(S)-3-Amino-3-(2-thienyl)-propionic acid

Form: C22H19NO4S

MW: 393.46

Cas. No: n.a.

 

CV1307

(R)-3-Amino-3-(1-naphthyl)-propionic acid

Form: C13H13NO2

MW: 215.25

Cas. No: 775280-91-6

CV1801

Boc-(R)-3-Amino-3-(1-naphthyl)-propionic acid

Form: C18H21NO4

MW: 315.37

Cas. No: 500789-00-4

 

CV2801

Fmoc-(R)-3-Amino-3-(1-naphthyl)-propionic acid

Form: C28H23NO4

MW: 437.49

Cas. No: 511272-47-2

 

CV1525

ethyl (R)-3-amino-3-(1-naphthyl)-propionate

Form: C15H17NO2

MW: 243.31

Cas. No: 275826-40-9

 

CV1308

(S)-3-Amino-3-(1-naphthyl)-propionic acid

Form: C13H13NO2

MW: 215.25

Cas. No: 275826-46-5

CV1802

Boc-(S)-3-Amino-3-(1-naphthyl)-propionic acid

Form: C18H21NO4

MW: 315.37

Cas. No: 500770-68-3

 

CV2802

Fmoc-(S)-3-Amino-3-(1-naphthyl)-propionic acid

Form: C28H23NO4

MW: 437.49

Cas. No: 507472-10-8

 

CV1526

ethyl (S)-3-amino-3-(1-naphthyl)-propionate

Form: C15H17NO2

MW: 243.31

Cas. No: n.a.

 

 

amines

Prod.  No.

Prod.  No.

Prod.  No.

Prod.  No.

 

CV0501

(R)-tetrahydrofurfurylamine

[(R)-2-(aminomethyl)tetrahydrofuran]

Form: C5H11NO

MW: 101.15

Cas. No: 7202-43-9

e.e.:  >98 %   

 

CV0502

(S)-tetrahydrofurfurylamine

[(S)-2-(aminomethyl)tetrahydrofuran]

Form: C5H11NO

MW: 101.15

Cas. No: 7175-81-7

e.e.: >98 %